{"id":15723,"date":"2017-06-22T15:00:34","date_gmt":"2017-06-22T20:00:34","guid":{"rendered":"http:\/\/panamaextrema.com\/pe\/?p=15723"},"modified":"2017-06-22T10:55:34","modified_gmt":"2017-06-22T15:55:34","slug":"descubren-tratamiento-oral-reduce-las-consecuencias-infarto","status":"publish","type":"post","link":"https:\/\/panamaextrema.com\/pe\/descubren-tratamiento-oral-reduce-las-consecuencias-infarto\/","title":{"rendered":"Descubren tratamiento oral que reduce las consecuencias de un infarto"},"content":{"rendered":"<p class=\"\">En un centro espa\u00f1ol, cient\u00edficos han demostrado a trav\u00e9s de un ensayo con ratas la efectividad de un tratamiento oral que reduce <b>las consecuencias del infarto de miocardio sobre la funci\u00f3n del coraz\u00f3n<\/b>, incluso si la medicaci\u00f3n se administra un d\u00eda despu\u00e9s del infarto.<\/p>\n<p class=\"\">El grupo liderado por <b>David Gac\u00eda-Dorado<\/b>, hizo pruebas con ratas, demostrando&nbsp;por primera vez que es posible la inhibici\u00f3n cr\u00f3nica de las calpa\u00ednas (unas enzimas activadas por el aumento del calcio intracelular) mediante un tratamiento oral que atenua los da\u00f1os en el coraz\u00f3n tras un infarto agudo de miocardio.<\/p>\n<p class=\"\">Para el estudio se utiliz\u00f3&nbsp;un modelo de infarto por oclusi\u00f3n coronaria transitoria en ratas para demostrar que las calpa\u00ednas persisten sobreactivadas durante las semanas siguientes a un infarto.<\/p>\n<blockquote><p>\u00abLa administraci\u00f3n oral diaria de un nuevo inhibidor de las calpa\u00ednas previene esta sobreactivaci\u00f3n, reduce el remodelado ventricular y mejora la funci\u00f3n contr\u00e1ctil a los 21 d\u00edas del infarto, resumi\u00f3 Javier Inserte, investigador del VHIR.<\/p><\/blockquote>\n<p class=\"\">De acuerdo con Inserte, el medicamento experimentado&nbsp;disminuye la hipertrofia, la fibrosis y la inflamaci\u00f3n en el miocardio no infartado.<\/p>\n<p>Seg\u00fan los investigadores, los resultados demuestran que este efecto protector de la inhibici\u00f3n de la calpa\u00edna es debido a la prevenci\u00f3n del efecto de la calpa\u00edna sobre mol\u00e9culas reguladoras de la expresi\u00f3n g\u00e9nica.<\/p>\n<p class=\"\">El infarto de miocardio es una de las principales manifestaciones&nbsp;de la cardiopat\u00eda isqu\u00e9mica.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>En un centro espa\u00f1ol, cient\u00edficos han demostrado a trav\u00e9s de un ensayo con ratas la efectividad de un tratamiento oral que reduce las consecuencias del infarto de miocardio sobre la funci\u00f3n del coraz\u00f3n, incluso si la medicaci\u00f3n se administra un d\u00eda despu\u00e9s del infarto. El grupo liderado por David Gac\u00eda-Dorado, hizo pruebas con ratas, demostrando&nbsp;por &hellip;<\/p>\n","protected":false},"author":2,"featured_media":15724,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[40],"tags":[],"class_list":["post-15723","post","type-post","status-publish","format-standard","has-post-thumbnail","","category-noticias"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Descubren tratamiento oral que reduce las consecuencias de un infarto &#171; PanamaExtrema.com<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/panamaextrema.com\/pe\/descubren-tratamiento-oral-reduce-las-consecuencias-infarto\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Descubren tratamiento oral que reduce las consecuencias de un infarto &#171; PanamaExtrema.com\" \/>\n<meta property=\"og:description\" content=\"En un centro espa\u00f1ol, cient\u00edficos han demostrado a trav\u00e9s de un ensayo con ratas la efectividad de un tratamiento oral que reduce las consecuencias del infarto de miocardio sobre la funci\u00f3n del coraz\u00f3n, incluso si la medicaci\u00f3n se administra un d\u00eda despu\u00e9s del infarto. 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